Hello Paolo,
Talking about IFrames and Android and iOS apps, I want to say something that may can be useful to you, because you must take it into your consideration. Commonly we must take care when deal with possible links inside our apps. This means that we must control all the links that we can place inside HTML controls, for example, handle it and don't leave the link to be opened "in a normal way". What we must to do, basically, is to handle the link and open it in a new window: it's possible to open it in the system's browser or in the browser provide to us by the Cordova "InAppBrowser" plugin.
Maybe it's not your case, however, we must handle the links because, if we don't handle it, they are opened inside our app's Webview, and, this can cause some problems. Not in all apps this problem appears, but, can appears in some specific apps. For example, supose we maintain an user session inside the app: if we allow the links to be opened in the app's Webview, when the user come back to the Webview, we can loss the app's variables, and, therefore, the user session (saved in that app's variables) is also loss. The solution is always the same: use the Cordova "InAppBrowser" plugin to handle the possible links and never allow the link to be opened in the app's Webview.
I want to mention this "link issues", which is not only related with AB, but, with any Apache Cordova app, because the IFrame usage can put us in a trouble if we need to handle the links... basically we can't do it... because the links which are inside the IFrame cannot be controlled outside the IFrame. So this means we cannot use an IFrame control in our apps? Not at all. We can use IFrames and sometimes they are quite useful, but, the content of the Iframe must be more or less know, and, for example, the links inside the IFrame cannot use a "target=blank" in the links, ni other words, all the links inside an IFrame must be opened in the same IFrame.
Again, maybe this is not a problem in your specific app: maybe the app don't rely in variables, so, maybe we can loss the control with a link who are opened in the app's Webview, and then, we can get back to the app without problems. However, I think that I must refer this possible problem in case you plan to use links to with "target=blank" in your IFrame's content. Because a "target=blank" means "open the link in a new window", and, this new window (for the IFrame) is the app's Webview itself. If your website, then, don't open links in new windows, there is no problem, because your website's links will be opened inside the IFrame, so you don't loss the control at all.
Please, post here if you have any questions or doubt about what I am trying to explain here around the possible link issues inside IFrames. I am not sure about what you are trying to do, so, I don't know if you need to use an IFrame (for example, you no need it if you want to post some information in your website's database, you can use an HTTP control to post it, or just use an XMLHttpRequest to do it). But, if you really want to use an IFrame, then you must take note about the links inside the IFrame's content: the links can be only opened inside the same IFrame / window, and, never have links with "target=blank", since the links will be opened in the app's Webview and this can cause some unexpected (in fact expected, but, anyway a non desired) behaviour.